Broiler intestine is colonised by diverse microbial count. It is niche of complex ecosystem formed by microbes. This microbial count affects hosts response to nutrient digestion & absorption, general physiology along with local or systemic immunological reaction. The gut micro flora is relatively stable in healthy poultry. However when major qualitative and quantitative changes occur in the gut microbial count, the broiler host can face dysbacteriosis by showing clinical signs such as diarrhea, flushing, diuresis.
Generally dysbacteriosis causes modifications in intestinal pH. Enteropathogenic bacteria like E.coli, salmonella grow in ileum & ceaca which produces toxins & metabolites increasing the gut motility, changing gut pH and irritation of the mucus membrane, which leads to inflammation and secretion of mucous. Enteropathogenic bacteria survive in slightly alkaline pH. But Herbofloxin maintains slightly acidic pH of average 6.8 in the gut. This gives 4 times reduction in Salmonella, E.coli, campylobacter count, thus maintaining the gut pH will help in reducing the Enteropathogenic bacterial count.