Is It Necessary To Premix?

Is It Necessary To Premix in livestock feedA premix is a blend of minerals, vitamins, feed supplements and diluents. The premix business is charged of the obligation of assembling a fantastic premix reliably, effectively and monetarily. The principle objective in feed mixing is to guarantee that an animal gets the majority of its figured supplement remittances consistently. Most sustain producers utilise the coefficient of variety (CV) to gauge blender execution and blend consistency. The CV is characterised as 100 * standard deviation/mean. A 5% CV is the business standard for generally fixings. An ingredient mix CV of 5% grants that an animal get no less than 90% of its planned dietary stipends 95% of the time. Be that as it may, the size of an adequate CV will change contingent upon the logical accuracy for measuring the fixing and the fixing proportion in the eating routine. The CV for a fixing test (repeatability of the explanatory system) ought to be not exactly the wanted CV for blender proficiency. With respect to ingredient ratio, the lower the ingredient concentration in the mix, the higher the CV.  Hence, the CV is generally higher for follow mineral, vitamins and medications in light of the fact that their fixing proportions are low (under 1:10,000).

A quality premix can be made just through a stringent quality affirmation program and current great assembling rehearses (cGMP). Quality affirmation is a proactive, persistent framework for observing reproducibility and dependability of an item. It incorporates all the activities undertaken to guarantee foreordained benchmarks of a quality premix. Good manufacturing practices covers covers all the areas of the production process like staff, offices, crude materials, quality affirmation checks, stock control, preparing, blending, packaging and conveyance.

Guidelines for feed formulation

1) Premix: Premix micro ingredients, for example, antibiotic growth promoters, vitamins, and minerals with a reasonable diluent before their consideration in a supplement. Diluents serve to dilute the micro ingredient and consequently encourage the rate of blending. Diluents ought to be dry with a specific end goal to allow a more uniform scattering of individual miniaturised scale fixing particles. Dampness must be maintained a strategic distance from as it might bring about entrainment and bunching (hygroscopic mixes, for example, urea are not appropriate diluents). Nonetheless, it can be preformed all the more effectively and proficiently by method for a small portable cylinder mixer (cement mixer). Defensive apparel, gloves and clean veil ought to be worn when when handling micro ingredients.

2) Supplement: This supplement will contain the premix, an appropriate Carriers, and the remaining minor dry ingredients in the diet routine including minerals, urea, and supplemental protein sources. Carriers are feed ingredients which join with the small scale fixings in the premix to change their physical attributes. By adsorbing to the carrier, the fine particles of the micro ingredients are permitted to move all the more quickly and consistently through the blend. This quick development of micro ingredients through the blend is vital to guarantee satisfactory dispersion before addition of molasses. The carriers ought to have physical properties practically identical to ground grain or oil seed dinners. For sure, both of these might be utilised as carriers. Be that as it may, the adsorptive properties of ground grain and oil seed suppers are low. This constraint might be overcome by first consolidating 2% fat to the ground grain or oil seed feast before mixing with the premix. In preparing the supplement, first include the carrier, and then include other major ingredients until they achieve the focal shaft line, then include the premix and other minor ingredients, lastly include the remaining major ingredients.

3) Finished feed: Finished feed might be prepared as follows: 1) include the grain portion of the diet to the blender; 2) add the dry supplement  to the centre of the blender (if possible, include supplement the inverse end of the blender to where the feed is released); 3) permit feed to blend for at least 1 minute; 4) add forage part of the diet; 5) add fat segment of the diet; 6) add molasses of the diet; 7) permit to blend for the time determined for the blender.

4) Adding Molasses: Molasses is a typical ingredient in diet formulation. However, it is very viscous and this introduces a few issues in feed mixing. Surely, if added to the diet despicably it can bring about marked increments in the CV of the micro ingredients. Dark strap molasses is especially viscous. The proficiency of mixing dark strap molasses with other dietary fixings will be improved in the event that it is initially weakened with water. The consistency of molasses is notably diminished by warming. Molasses ought not be warmed to temperatures in abundance of 43 degree Celsius, except for very short periods of time, as this may cause carmelization.

Here are some of the benefits of premixing

Accuracy of the weighting of the micro-ingredients

Micro-ingredients would require a much higher precision of weighting than macro-ingredients. That would request adjusted hardware that ought to be committed and set up particularly for micro-ingredients

Savings of blending time

As specified over, the preparation of premixes can decrease the preparing time. In fact, the weighting of the micro-ingredients can be extremely tedious and it would be more profitable to sort out this procedure in parallel to the preparation of the macro-ingredients.

Reduction of crossed contamination

The addition of diluted micro-ingredients into the system will leave lower traces than if the same micro-ingredients were incorporated pure. Also, it is simpler to clean up the premixing equipment because of its smaller size and easier access.

The Science of Feed Formulation

The Science of Feed FormulationFeed formulation requires top to bottom information of animal nutrition, especially the supplement necessities and the nutritional composition of the animal feed. It requires nutritionist with good knowledge of using certain proportions of some ingredients that affect on problems such as free flow through the mill, pellet quality of the diet, digestion of the animal feed or total gut well being of the animal.

Feed industry worldwide use 4 basic steps to produce animal feed.

  1. Receiving raw materials from supplier.
  2. Generating a feed formula based on previous authentic research.
  3. Blending all the ingredients together to prepare feed.
  4. Packaging and labelling feed to be shipped for commercial or retail purposes.

Quality control is an arrangement of methodology followed to guarantee quality of a product and all factors involved. Quality assurance starts with examination of incoming ingredients. Damage by heat, molds, climate, insects, adulterant and contaminants can be detected by trained technical supports. Blending quality can likewise be assessed quickly. The presence or absence of micro ingredients, minerals and vitamins are established by observation or by micro spot-testing.

Laboratory testing is a critical part of any quality control program since it quantifies particular segments of a feed/ingredient sample to guarantee that it meets quality determinations. Tests include physical, chemical, biological and other electronic measurements to determine the quality of product in contrast with a prescribed standard.

Liquid feed is used in dairy industry to feed cattle and provide a well-balanced mixture of nutritional supplements in a molasses base, which can be distributed in a feed taken or added to another form of feed, is that the proteins promote the probiotic microorganism in the rumen, which contribute to the breakdown of fiber and forage.

Feed manufacturers must follow regulations represented by the U.S. Food and Drug Administration. FDA is in charge of the regulation of feed and implementation of policies through the state government and the Association of American Feed Control Officials. Various feed certification programs—such as the American Feed Industry Association’s Safe Feed/Safe Food Certification Program— are likewise accessible for additional compliance and regulation.

Micro Emulsions in Poultry

Micro Emulsions in PoultryMicro emulsions in Poultry are dispersion’s of oil and water with an emulsifier. They are clear, thermodynamically stable, isotropic liquid mixtures. They are super solvents which improves stability and thermodynamic activity of formulation. Micro emulsions are beneficial to be used because it increases efficacy of the formulation allowing dose reduction. The average particle size of micro emulsion is 0.1 micrometer which helps in increasing the inter facial area thereby allowing active ingredient to get released easily. In poultry, micro emulsions are designed to include natural essential oils cell wall which in turn binds to mycotoxins to protect animals against mycotoxosis.

Vinayak Ingredients have introduced micro emulsion which is an alternative to antibioticsnamed as Herbofloxin. It is of natural origin prepared from essential oil of syzygium, citronella, thymus, eucalyptus. Herbofloxin has a particle size less than 0.1 micrometer which makes it easily soluble in water. It maintains poultry gut’s pH-6.5 to 6.7 which is slightly acidic. As it is a micro emulsion it has better dispersion in water, stable at 45 degree Celsius temperature and has a longer shelf life. All these factors makes it safe to be consumed by poultry without having any side effects which are otherwise usually caused by using antibiotics. Herbofloxin is natural replacer for antibiotic growth promoters.

Mechanism of action: Herbofloxin being a micro emulsion when mixed with water forms nano emulsion due to which particle size decreases further making it easier to penetrate the bacterial cell wall and disrupt it. Disruption of cell wall leads to killing of bad bacteria such as Escherichia coli, Campylobacter, Clostridium and Salmonella. Thus it acts like a bacteriostatic. It also acts as an anti-inflammatory by improving mucin coverage which is a first line of defence in poultry.

Herbofloxin as a micro emulsion replaces antibiotics such as tetracycline’s, fluoroquinolones, amino glycosides and selectively modulates poultry gut to promote the beneficial microflora.

Role of Antioxidants in Feed

Role of Antioxidants in FeedAntioxidants play a major role in animal health, production and performance. This is due to the detrimental effects of radicals and toxic products of their metabolism on various metabolic processes. It is a well known fact that oxidative stress is involved in many degenerative disorders. The oxidative free radicals are therefore considered as pathobiochemicals mechanism for initiating or progression of various diseases. The prooxidant-antioxidant balance can be regulated by optimal nutrient uptake or providing herbal antibiotics. Thus, the essential step in maintaining the balance between the oxidative damage and antioxidative defence in the animal body would be to boost the antioxidant capacity by optimising the dietary intake of antioxidants.

Vitamin C is a water-soluble antioxidant. It is an important anti-stress agent. However, it can be easily oxidized. Sources of vitamin C are citrus fruits and vegetables. Vitamin C is required in collagen biosynthesis and protein metabolism.

Vitamin E is the found in the biological membranes and lipid droplets. Vitamin E is absorbed in the small intestine with various efficacious depending on the diet composition, level of supplementation, age, sex and other individual characteristics of animals. It is the main chain-breaking antioxidant in biological systems.

Carotenoid is a natural pigment, responsible for yellow, orange and sometimes red pigmentation’s in plants, insects, birds and marine animals. They possess antioxidant activity. They have some health promoting properties, including immune system modulation. They are found in some plant-derived feed ingredients.

Manganese has an essential part of a range of enzymes taking part in antioxidant protection, bone growth and egg shell formation carbohydrate and lipid metabolism including processing of cholesterol.

Zinc is the second most abundant trace element trace element in mammals and they take part in antioxidant defence as an integral part of SOD, hormone secretion, keratin generation and epithelial tissue integrity immune function.

Iron has a vital role in antioxidant defence as an essential component of catalase, energy and protein metabolism, hence respiratory carrier, electron transport, oxidation-reduction reaction.

Gut Inflammatory Status in Poultry

Gut Inflammatory Status in PoultryThe gastrointestinal tract is the most exposed surface in the body and many diseases are largely related to the gut health status of the broiler. It is an important organ system as poor gut health results in poor nutrient assimilation. Some bacteria play an important role in helping broilers digest feed. Feed constituents affect the viscosity of the gastric content which helps in the development of small intestine micro-biota.  Any significant fluctuation in number or type of commensal leads to diarrhea which may cause severe damage to the intestine ultimately leading to poor performance and diseased birds. Dysbiosis that outnumbers good bacteria for which bad bacteria are then able exert their undesirable effects on the gut lining. Thus, to maintain good health and welfare farmers should focus on the integrity of the intestinal system.

Many causes lead to the loss of intestinal integrity such as:

  • Immuno-suppression: This can be caused due to viral diseases, vaccination or some disease challenges.
  • Antimicrobial activity: The use of antimicrobial growth promoters affect on bacteria can affect the natural micro flora of the intestine.
  • Environmental factors: Many clostridial spores or coccidia can persist despite harsh environmental conditions may gain infectivity later under favourable conditions.
  • Feed factors: Correct formulation of the diets plays critical role. Some of the ingredients such as enzyme incorrectly mixed or applied can have devastating consequences to intestinal integrity.
  • Water: Adequate supply of clean potable water is a norm. Any deviation in water quality has a direct effect on gut.

Disturbance in the intestinal integrity may affect health status and overall performance of birds in poultry production. Strategies such as prevention programs towards infectious disease and using alternatives to antibiotic are advisable replacing the existing chemical antibiotic to maintain intestinal homeostasis.

Herbofloxin-Natural Antibiotic Growth Promoter

Herbofloxin-Natural Antibiotic Growth Promoter

Herbofloxin is our answer to the long standing problem of antibiotic inclusions in feed and water of livestock. It is a unique micro emulsified formulation of phytoactive ingredients working as antibacterial, antiviral and antifungal solutions for monogastric organisms.

Herbofloxin eliminates chemicals such as, water sanitizers, pH regulators, feed disinfectants and antibiotics from Livestock production. It improves gut immune barriers to resist colonization by pathological microflora. Herbofloxin is a complete solution for providing a barrier against infective agents and safeguards the entry of zoonotic organisms in the food chain. Herbofloxin reduces gut colonization by E.coli, Salmonella and Campylobacter and thus reducing the zoonosis of the same in the meat. It is a growth promoter resulting in healthy weight gain.

Anti Antibiotics – The Way Ahead

Anti Antibiotics – The Way AheadFor years together Livestock has been an in separable part of humanity. The cheapest and most readily available source of protein.  The methods of rearing livestock have evolved in leaps; this is clearly evident in case of the poultry industry. The word broiler is now taken as Cobb or Ross and to keep up with the protein deficit of the world new strains are being introduced to cultivate meat faster and in an efficient way.

In this process several mechanisms have been devised to improve the bird, the environment or the final product. This introduces us to fields of Breeder genetics, Nutrigenomics, Housing, Management, Bio-security, Carcass traits, Packaging, Logistics and shelf life, all of which try to improve the profitability and the product quality.

The market is full of different feed additives working on the aspects latter to genetic improvement in breeders. For years antibiotics and specifically antibacterial have been used on a large scale to kick up revenues and cover up management flaws. Pumping in these drugs at these rates has resulted in the pathogenic bacteria being destroyed but also leads to the whole gastrointestinal micro floral balance instability. The era of misuse of antibiotics began. There are several views, as the use of antibiotics in livestock being good or bad. There are several reasons not to use antibiotics in livestock, the primary not being the antibiotic resistance but yes an important reason. Thus, apart from the common facts that using antibiotics may cause parallel resistance affecting human treatment regimes, it is also important for us to understand the foot print that antibiotics leave on the animal world.

The Livestock production arena is an amalgamation of bacterial opportunistic propagation driven entities. The race is already on between the eradication of these bacteria versus survival responses of these highly adaptive microbes. This is especially when we throw a cocktail of antibiotics on them. Every time zapping a bug with a new bullet does end the life of the bug, but also helps the bug to evolve a better armor, one that is non penetrable by the same bullet.  But why are we focusing on the bullet and not on the gun? Something that the bug may not even see, something that the bug is never exposed to!! The ideal route for restricting the excessive use of antibiotics is thus to improve the management practices on the farm which include impeccable bio-security. As this is not possible in all circumstances the use of anti-infective and growth promoters will always be used as a preventive and a treatment regime for under performing birds. However, we can always use a better trigger mechanism, there is middle way out. Why not use the natural responses of the bird itself fight the average management practices.

To improve the bird’s immunity and to overcome microbial challenges one should focus on certain specialised feed additives. The feed additive market carries an endless list of antibiotic re-placers which can be summarised in the categories of Acidifiers, Probiotics, Prebiotics and Phytobiotics. However, every trigger is only sensitive to a specific environment, a specific bacteria or a narrow mechanism of action. Acidifier resistance is well documented in recent literature, this with pH as low as 2.5 not proving effective against common taboo bacteria as salmonella. Probiotics work mainly in the finisher stages and farms still have to rely on antibiotics to curb the early chick mortality. Moreover, the probiotics work at variable dose with variable outcomes, some proving unsuitable to certain environments and ineffective in certain strains of poultry.  Prebiotics could have been an effective way to tackle the problem only if the cost and dosage would comply. Also there are various supportive nutrients fuelling the pathogenic bacteria in the gut which easily overcome prebiotics.  What the industry needs is something broad spectrum and natural. An effective Phytobiotic, and yes they work, but nobody wants to rely on a trigger that differs in sensitivity every time you are in a gunfight. What we really need is an effective and reliable Phytogenic antibiotic replacer which uses only standardised herbal Phytoconstituents as ingredients.