Avian coccidiosis is a deadly and debilitating infectious disease in poultry caused by obligate intestinal protozoan parasites belonging to the genus Eimeria. In general, these parasites damage the guts of the birds, leading to moderate clinical symptoms such as sick bird appearance, bloody stool, haemorrhage which ultimately results in intestinal lesions, enteritis, and even death. There are currently around 9 species of Eimeria identiﬁed from poultry, but each has a predilection site in the chicken digestive tract.
Eimeria primarily invades and resides in the lining of the caecum of exposed chickens. Infective sporozoites enter the caecal mucosa by penetrating villus epithelial cells, resulting in extensive destruction of the caecal epithelium,haemorrhagic faeces, reduction in body weight gain, and decrease in feed eﬃciency and eventually mortality which lead to serious economic consequences.
Current prophylaxis and therapy for coccidiosis comprise anticoccidial chemicals, vaccines, and natural products. Anticoccidial chemicals, coccidiocides, coccidiostats, and ionophores, have long been used as a mainstream strategy to control avian coccidiosis in modern poultry production. Although this strategy is cost-eﬀective and successful, the presence of drug resistance and public demands for residue free meat has encouraged development of alternative control strategies.
Plants are a rich source of phytochemicals against coccidiosis. BIOCOCCIN is a combination of phytochemicals with diverse mechanism of action on multiple species of Eimeria. These active constituents suppress the developmental stages in the lifecycle of Eimeria by several mechanisms which are summarized below.
- Prevenon of oocyst development
- Inhibion of sporulaon
- Inhibion of oocyst wall
- Destrucon of sporozoites in caeca
- Stabilizing intesnal structure and decreasing inflammaon
- Smulaon of immune response and modulaon
• Safe and compatible with all the feed ingredients and vaccines
• Acts on all major species of Eimeria
• Reduces number of coccidia to keep infection in check till immunity is established
• Reduces oocysts shedding
• Decreases intestinal inﬂammation
• Enhances immunity and antioxidant status